Guidelines for the prevention and treatment of opportunistic infections in adults and adolescents with HIV

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The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV document is published in an electronic format that can be easily updated as relevant changes in prevention and treatment recommendations occur.

The editors and subject matter experts are committed to timely changes in this document because so many health care providers, patients, and policy experts rely on this source for vital clinical information.

All changes are developed by the subject matter groups listed in the document (changes in group composition are also promptly posted). These changes are reviewed by the editors and by relevant outside reviewers before the document is altered.

Major revisions within the last 6 months are as follows:

  1. Coccidioidomycosis: Key updates to the guidelines include the following:
    • Revised section on serology for the diagnosis of coccidioidomycosis
    • Added PCR as a commercially available diagnostic test
    • Revised the section on patients who are asymptomatic with a positive serological test
  2. Bartonellosis: Key updates to the guidelines include the following:
    • Updated section on diagnostics, including role of PCR-based testing
    • Updated section on treatment for endocarditis
  3. Immunizations for Preventable Diseases in Adults and Adolescents Living with HIV: Key updates to the guidelines include the following:
    • Revised figure summarizing immunizations in PLWH
    • Added table comparing ACIP recommendations with Panel recommendations
    • Added narrative sections with evidence summaries
    • Updated recommendation for zoster vaccine

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