FDA approves trifluridine and tipiracil with bevacizumab for previously treated metastatic colorectal cancer

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On August 2, 2023, the Food and Drug Administration (FDA) approved trifluridine and tipiracil (Lonsurf Taiho Oncology, Inc.) with bevacizumab, for metastatic colorectal cancer (mCRC) previously treated with fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy, an anti-VEGF biological therapy, and if RAS wild-type, an anti-EGFR therapy.

FDA had previously approved single-agent Lonsurf for this indication in September 2015.

View full prescribing information for LONSURF

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