Person-centered choice and mHealth support for same-day delivery of long-acting injectable cabotegravir (ImPrEP CAB Brasil): a prospective, open-label, multicenter, quasi-experimental implementation study

This study (ImPrEP CAB Brasil) evaluated preferences for HIV pre-exposure prophylaxis (PrEP) options and the impact of an mHealth tool on informed decision-making among young, PrEP-naïve individuals in Brazil.

Among 1,447 participants, the majority (82.9%) chose long-acting injectable cabotegravir (CAB-LA) over oral PrEP, indicating a strong preference for this option. Participants who received the mHealth tool in addition to standard counseling were more likely to choose CAB-LA compared to those receiving standard counseling alone.

Higher levels of decisional conflict were associated with a lower likelihood of choosing CAB-LA. The mHealth tool was highly accepted, with most users reporting satisfaction and finding it helpful in supporting their decision.

Overall, the findings suggest that CAB-LA is highly preferred in real-world settings and that mHealth tools can effectively support informed PrEP choices. These results support the broader and more equitable implementation of CAB-LA in HIV prevention programs.

Additional information to the following link: https://www.thelancet.com/journals/lanam/article/PIIS2667-193X%2826%2900152-3/fulltext